But he said to me, 'My grace is sufficient for you, for my power is made perfect in weakness'" (2 Cor 12:9).
Have you ever done a job so well that you were promoted outside your skill set? The exceptional salesman gets promoted to manager and fails as a manager. The secretary gets promoted to office manager but fails for lack of management skills. Understanding your anointing will enable you to know when you are moving in a direction away from that which God has intended for your life.
I have seen this principle happen a lot over the years. There is a paradox between these two concepts that cannot be ignored. Sometimes God will place you in situations in which you have no natural gifting. In these cases, God puts you there to experience His power in order to accomplish your tasks.
When we yield to the leading of the Holy Spirit even though we may not have the physical abilities, God can teach us through his leading the gifts that will fit the job. Other times He is teaching us to acquire a new skill set for the given situation.